Oswestry Disability Index (ODI) | Basivertebral nerve ablation arm (N=66) | P value |
Baseline ODI | ||
Mean, SD (range) | 44.7, 11.3 (30–76) | |
9-Month ODI | n=60* | |
Mean, SD (Rrange) | 18.8, 16.4 (0 to –64) | |
Change from baseline, mean, SD | −25.6, 17.1 | <0.001† |
12-Month ODI | n=61* | |
Mean, SD (Rrange) | 18.6, 15.7 (0 to –60) | |
Change from baseline, mean, SD | −25.7, 18.5 | <0.001† |
9-Month Rresponder Rrate | n=60* | |
≥15-point ODI reduction, n (%) | 40 (66.7%) | 0.010‡ |
≥20-point reduction from baseline, n (%) | 35 (58.3%) | 0.197‡ |
12-Month Rresponder Rrate | n=61* | |
≥15-point ODI reduction, n (%) | 42 (68.9%) | 0.003‡ |
≥20-point reduction from baseline, n (%) | 37 (60.7%) | 0.096‡ |
Visual Analog Scale (VAS) |
Basivertebral nerve ablation arm
(n=66) | P value |
Baseline VAS | ||
Mean, SD (range) | 6.7, 1.3 (4–10) | |
9-Month VAS | n=60* | |
Mean, SD (Rrange) | 2.6, 2.5 (0 to –8) | |
Change from baseline, mean, SD | −4.0, 2.6 | <0.001† |
12-Month VAS | n=61* | |
Mean, SD (Rrange) | 2.9, 2.6 (0 to –8) | |
Change from baseline, mean, SD | −3.8, 2.6 | <0.001† |
9-Month Rresponder Rrate | n=60* | |
≥2 cm reduction, n (%) | 45 (75.0%) | <0.001‡ |
12-Month Rresponder Rrate | n=61* | |
≥2 cm reduction, n (%) | 48 (78.7%) | <0.001‡ |
Comparisons to baseline at 9 and 12 months for basivertebral nerve ablation arm patients were significant for both pain and function.
*As observed. No imputations for missing values.
†P value from a paired t-test (baseline to 9 and 12 months) for the BNV ablation arm.
‡P value from a binomial test.
ODI, Oswestry Disability Index; VAS, Visual Analog Scale.